4th World Sepsis Congress CME
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S2: The Health Economic and Human Burden of Infections and Pandemics
Course:
Hear from leading experts in the fields of epidemiology, social and humanity studies, intensive care, sustainable development policy and health economists, on the various multivalent human and socio-economic outcomes during wide-spread infections and pandemics.
Learning Objectives:
- Recognize the multifaceted short- and long-term impact sepsis has on various economic and human factors within societies.
- Understand the concept of universal health coverage and its relevance in achieving sustainable development goals within healthcare systems around the world.
- Realize ways in which universal health programs can be successfully adopted for improving healthcare quality and delivery outcomes.
Instructors:
- Keith Martin, Consortium of Universities for Global Health, United States of America (moderator)
- Carolin Fleischmann-Struzek, Jena University Hospital, Germany
- Syed Masud Ahmed, BRAC University, Bangladesh
- Tim Buchman, Emory University School of Medicine, United States of America
- Roy Small, United Nations Development Programme, United States of America
- Rob Yates, Chatham House, United Kingdom
S3: Overcoming Silos to Address Infection-Related Global Health Threats
Course:
A wide range of specialists will share paramount insights about health disparities that exist across different socioeconomic settings and how these discrepancies affect sepsis outcomes and other infection-related health crisis.
Learning Objectives:
- Understand the importance of collaborative efforts and having a multifunction cross-setting global team response to combat global health threats effectively.
- Recognize the need for cross-sector collaboration among various partners and organizations for improving quality of healthcare worldwide and improving outcomes through prevention and an accurate, timely response to infections and outbreaks.
- Acknowledge common examples of sepsis-related silos across various LMIC settings and patient groups and the impact these conceptions have on early treatment and proper sepsis management.
Instructors:
- Brenda Morrow, University of Cape Town, South Africa (moderator)
- Jyoti Joshi, International Centre for Antimicrobial Resistance Solutions, Denmark
- Mike English, Nuffield Department of Medicine, Oxford University, Kenya
- Ximena Garzón-Villalba, University San Francisco de Quito, Ecuador
- Catherine Machalaba, EcoHealth Alliance, United States of America
- Shevin Jacob, Liverpool School of Tropical Medicine, Uganda
S4: The Quality of Healthcare Systems and QI Efforts on Outcomes from Sepsis and Pandemics
Course:
A diverse group of skilled sepsis healthcare professionals share their knowledge and recommendations on how to improve sepsis care through the use of quality improvement initiatives across a multitude of care settings and regions.
Learning Objectives:
- Understand the impact unit-specific early patient deterioration methodologies with rapid response teams have on sepsis outcomes in various hospital settings.
- Recognize common inequalities that exist within various healthcare settings and the influence this has on sepsis-related care outcomes.
- Acknowledge the role sepsis mandates, digitalization and early response protocols have on improving quality of sepsis care.
Instructors:
- Gloria Rodríguez-Vega, University of Puerto Rico, Puerto Rico (moderator)
- Pierre Barker, Institute for Healthcare Improvement, United States of America
- Flavia Machado, Latin American Sepsis Institute, Brazil
- Daryl Jones, Austin Health, Australia
- Laura Evans, University of Washington, United States of America
- Joseph Bonney, African Federation for Emergency Medicine, Ghana
S6: Advances in Timely Pathogen and Sepsis Detection
Course:
Experts at the forefront of advanced diagnostic technologies share the latest updates, learnings and recommendations for a variety of comprehensive sepsis-pathogen detection methods, as well as novel biosensing and machine-enabled learning systems to aid in the rapid identification of sepsis.
Learning Objectives:
- Recognize how systematic differences in the health status of different population groups can affect the early identification of sepsis in various socioeconomic health settings.
- Understand novel findings in the field of sepsis-related biomarkers and how these advancements can potentially improve time to treatment and patient outcomes from sepsis.
- Learn about the role metagenomics has on sepsis sequencing and how new findings in the field of genetic analysis could improve early pathogen detection and accurate and timely treatment of sepsis.
- Perceive the impact of novel biosensing technologies and machine learning methodologies have on early detection of sepsis.
Instructors:
- Cheikh Tidiane Diagne, Institut Pasteur, Senegal (moderator)
- Amy Campbell, ECU Health, United States of America
- Elisa Estenssoro, Hospital Interzonal San Martin de La Plata, Argentina
- François Ventura, University Hospitals of Geneva, Switzerland
- Miriam Huntley, Day Zero Diagnostics, United States of America
- Tan Toh Leong, University Kebangsaan Malaysia, Malaysia
- Rishi Kamaleswaran, Emory University, United States of America
S7: The Benefits of Multidisciplinary Teams in Sepsis Care on the Health Care Facility Level
Course:
In this session, hear from healthcare professionals from Saudi Arabia, Zambia, Australia and the United Kingdom, about the impact and benefits of implementing sepsis-related quality care improvement programs using a multidisciplinary approach.
Learning Objectives:
- Recognize the relevance of utilizing a multidisciplinary approach and the steps needed for achieving successful quality improvement initiatives in both antibiotic stewardship and sepsis improvement programs withing the hospital setting.
- Understand the role nurses play and ways of inspiring and encouraging nurses, as well as other healthcare workers, in leading and working with multidisciplinary teams for the implementation of sepsis quality improvement projects.
- Learn why sepsis care must involve family members and home caretakers of septic patients.
- Perceive the importance of implementing mobility programs for ICU patients with sepsis and the impact these initiatives have on post sepsis patient outcomes.
Instructors:
- Karn Cliffe, Dublin Midlands Hospital Group, Ireland
- Yaseen Arabi, Ministry of National Guard Health Affairs, Saudi Arabia
- Mirfin Mpundu, Director of ReAct Africa, Zambia
- Amanda Harley, Children’s Health Queensland, Australia
- Kawaldip Sehmi, International Alliance of Patients’ Organization, United Kingdom
- Mohammed Alatwi, King Fahad Medical City, Saudi Arabia
S8: The Potential and Challenges to Intervene with the Immune Response
Course:
Learn more about the pathophysiology of sepsis and the various changes which occur at an immune system level; in addition to how current research findings on disease stratification could help in improving sepsis care through timely and endotype-tailored interventions.
Learning Objectives:
- Identify specific factors in both hosts and pathogens which can impact disease progression and patient outcomes.
- Acknowledge how the identification of endotypes based on inflammatory proteins in moderately ill patients with severe infection can be useful for patient stratification in sepsis.
- Understand the pathophysiology of common immune response pathways which occur during severe infections, and how advancements in the study of various proteins might help in targeting better treatment options for septic patients with severe infections.
- Comprehend what platform trials are and how they are used; in addition to learning about the possible pros and cons associated with such trails in the field of sepsis research.
Instructors:
- Nathan Nielsen, Global Sepsis Alliance, United States of America (moderator)
- Jennifer Muszynski, Nationwide Children’s, United States of America
- Mihai Netea, Radboud UMC, The Netherlands
- Evangelos J. Giamarellos-Bourboulis, European Sepsis Alliance, Greece
- Eirini Christaki, University of Ioannina, Greece
- Niels Riedemann, CEO InflaRx, Germany
S9: Biomarkers and Antimicrobial Stewardship – The Synergies to Diagnose Sepsis and to Prevent AMR
Course:
An in-depth look into synergies that exist between antimicrobial resistance and sepsis and how novel approaches to understanding biomarkers for early pathogen identification as well as widespread implementation of exemplary antimicrobial stewardship programs are essential in reducing the burden of sepsis through earlier recognition and accurate treatment response to infections.
Learning Objectives:
- Understand the global burden of antimicrobial resistance, the most common pathogens attributing to this burden, main drivers and factors impacting the development of AMR, and types of practices which can help reduce the incidence of AMR.
- Recognize common barriers to achieving antimicrobial stewardship and ways for incentivizing better sepsis care while regulating appropriate antibiotic consumption – through implementing integrated healthcare ecosystems which incorporate technological devices, patient and healthcare worker empowerment and seamless communication methods.
- Acknowledge how specific biomarkers may be used as indicators for the guide-lined use of antimicrobials in the treatment of sepsis.
- Comprehend the role various biomarkers and transcriptional diagnostic methods have on identifying risk classification and targeted therapy in septic patients, as well as their potential prognostic and predictive values in sepsis.
Instructors:
- Louise Thwaites, Global Sepsis Alliance, Vietnam (moderator)
- Silvia Bertagnolio, World Health Organization, Switzerland
- Ron Daniels, Infection Management Coalition, United Kingdom
- Evdoxia Kyriazopoulou, National and Kapodistrian University of Athens, Greece
- Peter Pickkers, Radboud UMC, The Netherlands
- Tom van der Poll, Amsterdam UMC, The Netherlands
S10: Lessons from the Pandemic to Fight Common Infections and Sepsis
Course:
Learn how findings from the recent COVID-19 pandemic have led to improvements in sepsis awareness globally, as well as our knowledge of sepsis management and ways of enhancing and providing comprehensive sepsis care.
Learning Objectives:
- Understand the role that public health and health and food safety organizations have in promoting and supporting an integrated health response in pandemic and other infectious disease outbreaks.
- Recognize how healthcare systems and public health authorities can respond more effectively to infectious diseases and sepsis in low- and middle-income resource-limited countries.
- Learn more about the developing role telehealth medicine has on supporting a more integrated approach to the treatment of sepsis in intensive care settings.
- Perceive novel ways for improving the care of critically ill patients in resource-limited settings by using new technologies and forging broader healthcare collaborationswhich can impact the diagnosis, treatment, and rehabilitation of sepsis and other infectious disease threats.
- Identify the importance and benefits of conducting large scale global clinical trials to address global health threats like sepsis.
Instructors:
- Detlev Ganten, Charité University Hospital, Germany (moderator)
- Benedetta Allegranzi, World Health Organization, Switzerland
- Velina Pendolovska, Directorate-General for Health and Food Safety, European Commission, Luxembourg
- John Adabie Appiah, African Sepsis Alliance, Ghana
- Wiltrud Abels, Sepsis Stiftung, Germany
- Louise Thwaites, Asia Pacific Sepsis Alliance, Vietnam
- John Marshall, Unity Health, Canada
S11: Understanding and Improving Long-term Outcomes After Sepsis and COVID-19
Course:
Learn about the various types of long-term sequelae both sepsis and COVID19 survivors experience, and how healthcare systems can help reduce implications associated with these long-term impacts through comprehensive and improved clinical care strategies.
Learning Objectives:
- Describe common long-term sequelae symptoms and associated demographics of sepsis and COVID-19 survivors.
- Learn about our current understanding around the pathogenesis behind long-term infections and sepsis.
- Understand the main driving factors for developing a more tailored medical care approach for sepsis patients and survivors in both children and adults, and what resources are needed to provide the best quality of care for sepsis survivors.
- List a number of impactful ways which can be utilized to encourage improved post sepsis care.
- Recognize successful, emerging system-based strategies for the recovery support of post sepsis and post covid survivors.
Instructors:
- Imrana Malik, Global Sepsis Alliance, United States of America (moderator)
- Jamie Rylance, World Health Organization, Switzerland
- Joost Wiersinga, Amsterdam UMC, The Netherlands
- Erin Carlton, University of Michigan, United States of America
- Hallie Prescott, University of Michigan, United States of America
- Stephanie Taylor, University of Michigan, United States of America
S12: Neonatal Sepsis Platforms and Guidelines
Course:
Neonatal sepsis experts provide a thorough understanding of the incidence and burden of neonatal sepsis globally, in addition to an overview of current management guidelines and areas of improvement, which could help mitigate better outcomes in neonatal sepsis, especially within low- and middle-income settings.
Learning Objectives:
- Recognize the burden antimicrobial resistance has on morbidity and mortality rates in neonates within low- and middle-income countries.
- Describe the scale of disease burden sepsis has in South Africa within the neonatal population.
- Identify common challenges faced in the management of neonatal sepsis in India.
- Recognize the burden bloodstream infections and antimicrobial resistance has across Africa, along with possible identified approaches to address these challenges and improve healthcare delivery methods.
Instructors:
- Odiraa Nwankwor, Sidney Kimmel Medical College, United States of America (moderator)
- Ramanan Laxminarayan, University of Washington, United States of America
- Vanessa Quan, National Institute for Communicable Diseases, South Africa
- Jeeva Sankar, All India Institute Of Medical Sciences, India
- Uduak Okomo, MRC Unit, The Gambia
- Julia Bielicki, St George’s University of London, United Kingdom
S14: Maternal Sepsis: Why Is It Still in the Top 3 for Global Incidence of Sepsis?
Course:
Professionals in the field of maternal health provide an in-depth view into the current state of maternal sepsis globally, including level of sepsis awareness, current clinical guidelines and methods for early detection which may be used across different income settings to improve the burden of disease around the world.
Learning Objectives:
- Understand the global epidemiological overview of maternal sepsis, estimated incidence rates across various regions and the impact it has on families, healthcare systems and societies.
- Recognize the impact sepsis awareness has on clinical outcomes and necessary steps for enhancing advocacy initiatives globally to reduce the burden of maternal sepsis.
- Identify effective methods for the early detection and timely management of maternal sepsis, and the resulting improvements in morbidity and mortality rates this may have.
- Learn how changes in socioeconomic systems can impact health care coverage and public health access through improving organizational structures.
- Perceive the WHO´s recommendations and efforts to address the burden of maternal sepsis.
Instructors:
- Mercedes Bonet, World Health Organization, Switzerland (moderator)
- Alan Tita, University of Alabama at Birmingham, United States of America
- Helen Cheyne, University of Stirling, United Kingdom
- Maria Fernanda Escobar Vidarte, The International Federation of Gynecology and Obstetrics, Colombia
- Edgardo Abalos, Independent Researcher, Argentina
- Sabina Abou Malham, Université de Sherbrooke, Canada
- Benedetta Allegranzi, World Health Organization, Switzerland
S16: An Update on Research on Sepsis
Course:
Leading researchers from across the world share an extensive overview of leading and highly relevant global research studies within the field of sepsis.
Learning Objectives:
- Understand the current research around a consensus approach and the standardization of diagnostic criteria for defining sepsis in children will be paramount in our healthcare systems´ ability to provide enhanced early recognition and improved management of sepsis in children.
- Recognize the impact of source control and time to intervention can have on patient outcomes and sepsis mortality rates as identified through recent retrospective data analysis studies.
- Outline the relationship between time to antibiotic administration in sepsis and possible implications this may have on antimicrobial resistance and stewardship.
- Identify the impact administering intravenous Vitamin C Therapy had on patients with sepsis.
- Learn more about various fluid resuscitation therapies used in the management of septic patients and the outcomes observed on morbidity and mortality rates.
Instructors:
- Mercedes Bonet, World Health Organization, Switzerland (moderator)
- Alan Tita, University of Alabama at Birmingham, United States of America
- Helen Cheyne, University of Stirling, United Kingdom
- Maria Fernanda Escobar Vidarte, The International Federation of Gynecology and Obstetrics, Colombia
- Edgardo Abalos, Independent Researcher, Argentina
- Sabina Abou Malham, Université de Sherbrooke, Canada
- Benedetta Allegranzi, World Health Organization, Switzerland