An in-depth look into synergies that exist between antimicrobial resistance and sepsis and how novel approaches to understanding biomarkers for early pathogen identification as well as widespread implementation of exemplary antimicrobial stewardship programs are essential in reducing the burden of sepsis through earlier recognition and accurate treatment response to infections.

Learning Objectives:

• Understand the global burden of antimicrobial resistance, the most common pathogens attributing to this burden, main drivers and factors impacting the development of AMR, and types of practices which can help reduce the incidence of AMR.
• Recognize common barriers to achieving antimicrobial stewardship and ways for incentivizing better sepsis care while regulating appropriate antibiotic consumption – through implementing integrated healthcare ecosystems which incorporate technological devices, patient and healthcare worker empowerment and seamless communication methods.
• Acknowledge how specific biomarkers may be used as indicators for the guide-lined use of antimicrobials in the treatment of sepsis.
• Comprehend the role various biomarkers and transcriptional diagnostic methods have on identifying risk classification and targeted therapy in septic patients, as well as their potential prognostic and predictive values in sepsis.

Instructors:

• Louise Thwaites, Global Sepsis Alliance, Vietnam (moderator).
• Silvia Bertagnolio, World Health Organization, Switzerland.
• Ron Daniels, Infection Management Coalition, United Kingdom.
• Evdoxia Kyriazopoulou, National and Kapodistrian University of Athens, Greece.
• Peter Pickkers, Radboud UMC, The Netherlands.
• Tom van der Poll, Amsterdam UMC, The Netherlands.